Yuxin Li, Doctor degree, Associate professor, Institute of Elemento-organic Chemistry, graduated from Nankai University.

Special Talent：

Email：liyx128@nankai.edu.cn

Research Group Website：

1. Studies of Insect Physiology and Toxicology Using Fluorescent Patch Clamp 

2.Reational Discovery of Green Pesticides

1993-1996 Qingdao University

2000-2003 Hunan University of Science and Technology, MS

2003-2006 the institute of Elemento-Organic Chemistry, Ph.D

2006-2010 the institute of Elemento-Organic Chemistry, Tutor

2011-present the institute of Elemento-Organic Chemistry, Associate Professor

2015-2016 University of Florida, Visiting Scholar

Honors and Awards:

2004, First Prize of Qiushi Scholarship，Nankai University.

2005, Ruyu Chen Scholarship

2006, Excellent Graduated Graduate Student 

1）Zhao Y.Y., Gao L., Li H.G., Sun P.W., Meng F.F., Zhang Y., Xie Y.T., Sun B.Q., Zhou S., Ma Y., Xiong L.X., Yang N, Li Y.X.⁎, Li Z.M.⁎. Synthesis, insecticidal activities, and structure−Activity relationship of phenylpyrazole derivatives containing a fluoro-substituted benzene moiety. J. Agric. Food Chem., 2020, 68: 11282−11289. 

2）Wu C.C., Yu X. B., Wang B. L., Yu, Liu J.B., Meng F.F., Zhao Y.Y., Xiong L. X., Yang N, Li Y.X.⁎, Li Z.M.⁎. Synthesis, insecticidal evaluation, and 3D-QASR of novel anthranilic diamide derivatives containing N‑arylpyrrole as potential ryanodine receptor activators. J. Agric. Food Chem., 2020, 68: 9319−9328. 

3）Zhao Y. Y., Li H. G., Sun P.W., Gao L., Liu J.B., Zhou S., Xiong L. X., Yang N, Li Y.X.⁎, Li Z.M.⁎. Synthesis, biological activities, and SAR studies of novel 1-(2-chloro-4,5-difluorophenyl)-1H-pyrazole derivatives. Bioorg. Med. Chem. Lett., 2020, 30: 127535.

4）Li Z.Z., Jiang H., Liu S. N., Li Y.X.*, Yuchi Z.G.*, Gao Q.Z.*. Ryanodine receptor-targeting small molecule fluorescent probes enables non-isotopic labeling and efficient drug screening for green insecticides. Analytica Chimica Acta, 2020, 1108: 108-117. 

5）Li F. Y., Wang Y.H., Liu J.B.*, Li Y.X.⁎. Synthesis, insecticidal evaluation and mode of action of novel anthranilic diamide derivatives containing sulfur moiety as potential ryanodine receptor activators. Bioorg. Med. Chem., 2019, 27：769-776. 

6）Zhou Y.Y.*, Wei W., Zhu L.L., Li Y.X.⁎. Synthesis and bioactivities rvaluation of novel anthranilic diamides containing N-(tert-butyl)benzohydrazide moiety as potent ryanodine receptor activator. Chin. J. Chem., 2019, 37: 605—610.

7）Liu J.B., Li F.Y., Wang Y.H., Zhang H.X., Dong J.Y., Sun P.W., Li Y.X.*, Li Z.M.*. Synthesis, biological activities and 3D-QSAR studies of (R)-2-phenyl-4,5-dihydrothiazole-4-carboxamide derivatives containing a sulfur ether moiety. Chin. Chem. Lett., 2019, 30: 668-671. 

8）Chen W.*, Li Y.X., Zhou Y.Y., Ma Y., Li Z.M.. Design, synthesis and SAR study of novel sulfonylurea derivatives containing arylpyrimidine moieties as potential anti-phytopathogenic fungal agents. Chin. Chem. Lett., 2019, 30: 2160-2162. 

9）Liu J.B., Li F.Y., Li Y.X.*, Zhang X.L., Hua X.W., Xiong L.X., Li Z.M.*. Synthesis, insecticidal evaluation and 3D-QSAR study of novel anthranilic diamide derivatives as potential ryanodine receptor modulators. Pest Manag. Sci.. 2019, 75: 1034–1044. 

10）Liu J.B., Li F.Y., Dong J.Y., Li Y.X.⁎, Zhang X.L., Wang Y.H., Xiong L.X., Li Z.M.⁎,  Anthranilic diamides derivatives as potential ryanodine receptor modulators: synthesis, biological evaluation and structure activity relationship. Bioorg. Med. Chem., 2018, 26：3541–3550. 

11）Zhou Y.Y., Wei W., Zhu L.L., Li Y.X.*, Li Z.M.*. Synthesis and insecticidal activity study of novel anthranilic diamides analogs containing a diacylhydrazine bridge as effective Ca2+ modulators. Chem. Biol. Drug Des., 2018, 92:1914–1919.

12）Cheng D.D., Wei W., Li Y.X.* , Hua X.W., Zhou Y.Y., Liu J.B., Li Y.H., Yu S.J., Xiong L.X., Li Z.M.*，Design, synthesis and biological activities of novel 4,5-disubstituted-3-S- (β-D-acetylglycosyl)-1,2,4-triazole derivatives. Chem. Res. Chin. Univ., 2017, 33(5): 758-764.  

13）Liu J.B., Li Y.X.*, Zhang X.L., Hua X.W., Wu C.C., Wei W., Wan Y.Y., Cheng D.D., Xiong L.X., Yang N., Song H.B., Li Z.M.*，Novel anthranilic diamide scaffolds containing N substituted phenylpyrazole as potential ryanodine receptor activators. J. Agric. Food Chem., 2016, 64: 3697−3704. 

14）Li Y.X.*, Lian X.H., Wan Y.Y., Wang D.Y., Chen W., Di F.J., Wu W.J., Li Z.M.*，Modulation of the Ca2+ signaling pathway by celangulin I in the central neurons of Spodoptera exigua. Pestic. Biochem. Phys., 2016, 127: 76-81. 

15）Wan Y.Y., Wei W., Chen Y.W., Liu J.B., Cheng D.D., Xiong L.X., Yu S.J., Li Y.X.*, Li Z.M.*, Synthesis and bioactivity of (S, S)-2,8-diazabicyclo [4.3.0] nonane containing benzimidazole moiety. 农药学学报, 2016, 18(3): 291-298.  

16）Li Y.X.*, Di F.J., Wang D.Y., Chen W., Wan Y.Y., Li Z.M.*，Design and synthesis of 1-glycosyl-4-{N-[(2′-morpholinethoxy)-phenyl]aminomethyl}-1H-1,2,3-triazoles as calcium activators. Chem. Res. Chin. Univ., 2015, 31(6): 952-957.

17）Liu J.B., Li Y.X.*, Chen Y.W., Hua X.W., Wan Y.Y., Wei W., Song H.B., Yu S.J., Zhang X., Li Z.M.*. Design, synthesis, antifungal activities and SARs of (R)-2-aryl-4,5-dihydrothiazole -4-carboxylic acid derivatives. Chin. J. Chem., 2015, 33(11): 1269-1275. 

18）Zhou Y.Y., Wang B.L., Di F.J., Xiong L.X., Yang N., Li Y.Q., Li Y.X.*, Li Z.M.*，Synthesis and biological activities of 2,3-dihydro-1,3,4- oxadiazole compounds and its derivatives as potential activator of ryanodine receptors. Bioorg. Med. Chem. Lett., 2014, 24(10): 2295-2299.

19）Mao M.Z., Li Y.X., Zhou Y.Y., Zhang X.L., Liu Q.X., Di F.J., Song H.B., Xiong L.X., Li Y.Q., Li Z.M.*，Synthesis and insecticidal evaluation of novel N‑pyridylpyrazole carboxamides containing an amino acid methyl ester and their analogues. J Agric. Food Chem., 2014, 62:1536−1542. 

20）Mao M.Z., Li Y.X.*, Zhou Y.Y., Yang X.P., Zhang X.L., Zhang X., Li Z.M.*. Synthesis and biological activity of novel 1-substituted phenyl(glycosyl)-4-{4-[(4,6-dimethoxy)pyrimidin-2-yl]piperazin-1-yl}methyl-1H-1,2,3-triazoles. Chem. Res. Chin. Univ. 2013, 29(5): 900—905.

21）Mao M.Z., Li Y.X*., Liu Q., Zhou Y.Y., Zhang X., Xiong L.X., Li Y.M., Li Z.M.*. Synthesis and Insecticidal Evaluation of Novel N- pyridylpyrazole carboxamides Containing Cyano Substituent in the ortho-position. Bioorg. Med. Chem. Lett., 2013, 23(1): 42-46.

22）Zhou Y.Y., Li Y.X.*, Li Y.M., Yang X.P., Chen W., Mao M.Z., Liu T.W., Xiong L.X., Li Z.M.*, Design, synthesis and structure-activity of N-glycosyl-1-pyridyl-1H-pyrazole -5-carboxamide as inhibitors of calcium channel. Chem. Res. Chin. Univ., 2013, 29(2): 249-255.

23）Zhou Y.Y., Feng Q., Di F.J., Liu Q.X., Wang D.Y., Chen Y.W., Xiong L.X., Song H.B., Li Y.X.*, Li Z.M.*. Synthesis and insecticidal activities of 2,3-dihydroquinazolin-4(1H)-one derivatives targeting calcium channel, Bioorg. Med. Chem., 2013, 21: 4968–4975. 

24）Zhang J.F., Xu J.Y., Wang B.L, Li Y.X.*, Xiong L.X., Li Y.Q., Ma Y., Li Z.M.*. Synthesis and insecticidal activities of novel anthranilic diamides containing acylthiourea and acylurea，J. Agric. Food Chem., 2012, 60(31): 7565-7572. 

25）Yan T., Li Y.X. *, Li Y.Q., Wang D.Y., Chen W., Liu Z., Li Z.M.*，Synthesis and insecticidal activities of novel phthalic acid diamides. Chin. J. Chem., 2012, 30(7): 1445-1452.

26）Mao M. Z., Li Y. X.*,Zhou Y. Y., Chen W., Liu T. W., Yu S. J.,Wang S. H., Li Z. M.*. Synthesis and biological activity of novel 1-substituted phenyl-4-[N-[(2-morpholinothoxy) phenyl]aminomethyl]-1H-1,2,3-triazoles, Chem. Biol. Drug. Des., 2011, 78: 695-699.

27）Li Y.X., Mao M.Z., Li Y.M.*, Xiong L.X., Li Z.M., Xu J.Y., Modulations of high-voltage activated Ca2+ channels in the central neurones of Spodoptera exigua by chlorantraniliprole. Physiol. Entomol., 2011, 36: 230–234. 昆虫二区

28）Li Y.X.*, Chen W., Yang X.P., Yu G.P., Mao M.Z., Zhou Y.Y., Liu T.W., Li Z.M.*, Regioselective synthesis of novel 3-thiazolidine acetic acid derivatives from glycosido ureides. Chem. Biol. Drug. Des., 2011, 78: 969–978.