(1)Organophosphorus Chemistry .

(2)Organic Synthetic Chemistry

(3)Heteroatom Organic Chemistry

Education:

1982-1986 Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received B. Sc. Degree in June, 1986

1986-1989 Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received M. Sc. Degree in June, 1989

1994-1997 Department of Chemistry, Zhejiang(Hangzhou) University, Hangzhou, CHINA Received Ph.D. degree in June, 1997 (with Prof. Yongmin Zhang).

Academic Career:

1989-1994 Assistant professor and Lecturer, Department of Chemistry, Henan Normal University, Xinxiang, CHINA.

1997-1999 Postdoctoral associate, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA. (with Professor Ruyu Chen).

1999-2002 Postdoctoral associate, Graduate School of Pharmaceutical Sciences,Osaka University, Osaka, Japan. (with Professor Hidenobu Ohmori and Hatsuo Maeda)

2002-2008 Associate Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2008-2011 Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2011- Professor, State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

Selected publications：

1. DABCO-Mediated [4 + 4]-Domino Annulation: Access to Functionalized Eight-Membered Cyclic Ethers

Liang, Ling; Li, Erqing; Dong, Xuelin; Huang You

Org. Lett. 2015, 17(19), 4914?4917.

2. Highly Enantioselective Intermolecular Cross Rauhut–Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst

Dong, Xuelin; Liang, Ling; Li, Erqing and Huang You

Angew. Chem. Int. Ed. 2015, 54, 1621-1624. （Hot Paper）

3. Divergent Phosphine-Catalyzed [2+4] or [3+2] Cycloaddition Reactions ofγ-Substituted Allenoates with Oxadienes

Li, Erqing; Chang, Meijia; Liang, Ling and Huang You

Eur. J. Org. Chem. 2015, 710–714. （Hot Paper)

4. Morita–Baylis–Hillman adduct derivatives (MBHADs): versatile reactivity in Lewis base-promoted annulation

Xie, Peizhong and Huang You

Org. Biomol. Chem. 2015, 13(32), 8578–8595

5. A Sulfur Ylides-Mediated Domino Benzannulation ******** to Construct Biaryls, Alkenylated and Alkynylated Benzene Derivatives

Gao Fei and Huang, You

Adv. Synth. Catal. 2014, 356, 2422-2428.

6. Phosphine-catalyzed Domino Reaction: A Novel Sequential [2+3] and [3+2] Annulation Reaction of γ-Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives.

Li, Erqing; Huang, You*

Chem. Commun., 2014, 50 (8), 948-950.

7. Sequential Catalyst Phosphine/Secondary Amine-Promoted [1+4]/ Rearrangement Domino Reaction for the Construction of (2H)-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene Skeletons

Xie, Peizhong; Yang, Jie; Zheng, Jie; Huang, You*

Eur. J. Org. Chem., 2014, 1189-1194.

8. Phosphine-Catalyzed Domino Reaction: A Novel Method Access to Functionalized

Bicyclic Skeletons

Li, Erqing; Huang, You*

Chem. Eur. J., 2014, 20, 3520

9. Phosphine Initiated Domino Reaction: A Convenient Method for the Preparation of Spiro-cyclopentanones

Liang, Ling; Li, Erqing; Xie, Peizhong; Huang You*

Chem. Asian J. 2014, 9(5), 1270-1273

10. Phosphine-Catalyzed Sequential [2 +3] and [3 + 2] Annulation Domino Reaction of γ- Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3, 3, 0]octane Derivatives

Li, Erqing; Jia, Penghao; Liang, Ling; Huang, You*

ACS Catal. 2014, 4, 600?603.

11. A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition

Xu, Da-Zen; Zhan, Ming-Zhe; Huang, You*

Tetrahedron 2014, 70, 176-180

12. One step Synthesis of Benzoxazepine Derivatives via a PPh3 Catalyze aza-MBH Domino Reaction between Salicyl N-tosylimines and Allenoates.

Zhao, Hongxia; Meng, Xiangtai; Huang, You*

Chem. Commun., 2013, 49(89), 10513-10515.

(Highlighted by Prof. Snieckus, V and Guimar?es, K. G. in Synfacts 2014, 10(1), 0027)

13. Phosphine-Catalyzed Domino Reaction: An Efficient Method for the Synthesis of Bicyclo[3.2.0]heptenes Skeleton.

Zheng, Jie; Huang, You*; Li, Zhengming

Org. Lett. 2013, 15(22), 5758-5761.

14. Phosphine-Catalyzed Domino Benzannulation: An Efficient Method to Construct Biaryl Skeletons.

Zheng, Jie; Huang, You*; Li, Zhengming

Org. Lett. 2013, 15(19), 5064-5067.

15. Phosphine-Catalyzed [4+2] Annulation of gamma-Substituent Allenoates: Facile Access to

Functionalized Spirocyclic Skeletons.

Li, Erqing; Huang, You*; Liang, Ling; Xie Peizhong

Org. Lett. 2013, 15(12), 3138-3141.

16. Tunable Phosphine-Mediated Domino Reaction: Selective Synthesis of 2,3-Dihydrofurans and Biaryls

Xie, Peizhong; Li, Erqing; Zheng, Jie; Li, Xin; Huang, You*; Chen, Ruyu

Adv. Synth. Catal. 2013, 355(1), 161 – 169. （Hot Paper)

17. Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates.

Li, Erqing; Xie, Peizhong; Yang, Lihua, Liang Ling, Huang You*.

Chem. Asian J. 2013, 8(3) , 603-610.

18. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile ******** for the Construction of Carbocyclic Spirooxindoles Skeletons

Hu, Chongchong; Zhang, Qinglong; Huang, You*

Chem. Asian J. 2013, 8(9) , 1981-1984

19. Domino Cyclization Initiated by Cross-Rauhut-Currier Reactions

Xie, Peizhong; Huang, You*

Eur. J. Org. Chem. 2013, (20), 6213–6226.

20. Sulfur Ylides Participating Domino Cyclization Reaction.

Li Gongchun; Wang Liye; Huang You*

Chin. J. Chem. 2013, 33(9), 1900-1918.

21. Phosphine-catalyzed Domino Reaction: an Efficient Method for the Synthesis of Highly Functionalized Spirooxazolines.

Yang, Lihua; Xie, Peizhong; Li, Erqing; Li, Xin; Huang, You*; Chen, Ruyu

Org. Biomol. Chem. 2012, 10(37), 7628-7634.

22. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile ******** for the Construction of Highly Functionalized Cyclopentene.

Hu, Chongchong; Geng, Zhishuai; Ma, Jianze; Huang, You*; Chen, Ruyu

Chem. Asian J. 2012, 7(9) , 2032-2035.

23. Phosphine-mediated Domino Benzannulation ******** for the Construction of Highly Functionally Multi-aryl Skeletons

Xie, Peizhong; Huang, You*; Chen, Ruyu

Chem. Eur. J. 2012, 18(24), 7362-7366 (Most accessed article 2012.5)

24. Phosphine-Catalyzed Domino Reaction for the Synthesis of Conjugated 2,3-Dihydrofurans from Allenoates and Nazarov Reagents and the Mechanism Investigation

Xie, Peizhong; Lai, Wenqing; Geng Zhishuai; Huang, You*; Chen, Ruyu

Chem. Asian J. 2012, 7(7) , 1533-1537

25. Bifunctional phosphine-catalyzed Cross-Rauhut-Currier/Michael/Aldol Condensation Triple Domino Reaction: Synthesis of Functionalized cyclohexenes.

Xie, Peizhong; Huang, You*; Lai, Wenqing; Meng, Xiangtai; Chen, Ruyu.

Org. Biomol. Chem. 2011, 9(19), 6707-6714.

26. Domino Reaction for the Chemo- and Stereoselective Synthesis of Trans-2,3-Dihydrobenzofurans from N-Thiophosphinyl Iimines and Sulfur Ylides.

Xie, Peizhong; Wang, Liye; Yang, Lihua; Li, Erqing; Ma, Jianze; Huang, You*; Chen, Ruyu.

J. Org. Chem. 2011, 76(19), 7699-7705

27. Substrate-Controlled Phosphine-Catalyzed Domino Reactions of Activated Conjugated Dienes: Highly Diastereoselective Synthesis of Bicyclic Skeletons.

Ma, Jianze; Xie, Peizhong; Hu, Chongchong; Huang, You*; Chen, Ruyu.

Chem. Eur. J. 2011, 17(27), 7418-7422 （Hot Paper)

28. N-Heterocyclic Carbene-Catalyzed (NHC) Three-Component Domino Reactions: Highly

Stereoselective Synthesis of Functionalized Acyclic ε-Ketoesters.

Ma, Jianze; Huang, You*; Chen, Ruyu.

Org. Biomol. Chem. 2011, 9(6), 1791-1798

29. Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Ssynthesis of Trans-2,3-Dihydrobenzofurans from Salicyl N-Thiophosphinyl Imines and Allylic Carbonates.

Xie, Peizhong; Huang, You*; Chen, Ruyu.

Org Lett. 2010, 12(17), 3768-3771.

30. PPh3-Catalyzed Domino Reaction: A Facile Method for the Synthesis of Chroman Derivatives.

Meng, Xiangtai; Huang, You*; Zhao, Hongxia; Xie, Peizhong; Ma, Jianze; Chen, Ruyu.

Org. Lett. 2009, 11(4), 991-994.

31. Bifunctional Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis of cis-2,3-Dihydrobenzofurans from Salicyl N-Thiophosphinyl Imines and Allenes.

Meng, Xiangtai; Huang, You*; Chen, Ruyu.

Org Lett. 2009, 11(1), 137-140.

32. A Novel Selective aza-Morita-Baylis-Hillman (aza-MBH) Domino Reaction and aza-MBH Reaction of N-Sulfonated Imines with Acrolein Catalyzed by a Bifunctional Phosphine Organocatalyst.

Meng, Xiangtai; Huang, You*; Chen, Ruyu.

Chem. Eur. J. 2008, 14(23), 6852-6856.（Hot Paper， Most accessed article 2008.7)

Groups：

Current Ph. D. Students: Li Ning，Feng Jiaxu, Chen Junlong, Zhu Yannan, Cai Wei， Zhou Yiming

Current Masters Students: Wang Dan, Lai Jingxiong, Lin Junhui

Current Undergraduate Students: Chen Yu, Chen YIngying, Qin Wenhui

Former Students:

Ph.D.

Meng Xiangtai(2009)

Xie Peizhong(2013)

Zheng Jie(2014)

Li Erqing(2015)

Dong Xuelin(2015)

Liang Ling(2016)

Zhang Qinglong(2017)

Jia Penghao(2018)

Jin Hongxing(2019)

M.S.：

Feng Dexin(2004)

Gu Yingchun(2006)

Wang Jinliang(2006)

Yu Yaqin(2007)

Xu Dazhen(2008)

Zhang Kui(2009)

Cui Meng(2009)

Zhao Hongxia(2010)

Shao Yongchen(2010)

Ma Jianze(2011)

Xiong QinPing(2011)

Wang Liye(2012)

Yang Lihua(2012)

Hu Chongchong(2013)

Gao Fei(2014)

Yang Jie(2015)

Chang Meijia(2016)

Wu Chengzhou(2017)

Yin Zhongmo(2018)

B.S.：

Xu Dazhen(2004)

Pan Lu(2005)

Zou Guanjun(2005)

Zhao Hongxia(2006)

Han Bailiang(2007)

He Dongming(2007)

Liu Tanglin(2008)

Lai Wenqing(2010)

Chen Yuchen(2010)

Geng Zhishuai(2012)

Chen Kaihong(2013)

Zheng Yanming(2015)

Li Ning(2016)

Zhang Yan(2016)

Tang Qingxuan(2017)

Xiu Wen(2017)

Wang Dan(2018)

Zhu Ziqi(2018)

Dai Changhang(2019)